Research Grants

//Research Grants
Research Grants 2017-11-13T10:36:47+00:00

With obesity at epidemic proportions worldwide, obesity research has become a much needed area of study. The ASMBS Foundation is helping to solve the obesity problem by sponsoring scientific research grants concerning bariatric surgical procedures and improvement of post surgical outcomes. Recognizing the escalation in obesity and the extraordinary difficulties in its prevention and treatment, the ASMBS Foundation is working with the ASMBS to take important steps to augment obesity research.

Grants funded by the ASMBS Foundation

Matthew Fourman, MD, FACS

Grant Title:
Surface Electromyography (EMG) as a Measure of Surgeon Muscle Fatigue During Robotic and Laparoscopic Bariatric Surgical Procedures

Currently in progress

Jayleen Grams, MD, FACS, PhD

Grant Title:
Skeletal Health and Bariatric Surgery Patients

Currently in progress

Michel Murr, MD, FACS

Grant Title:
RYGB Improves Insulin Resitance via Sirt-1 and Gas5

Currently in progress

Lauren Bradley, PhD

Grant Title:
The Investigation of a Remotely Delivered Behavioral Intervention for Postoperative Weight Regain

Currently in progress

Tammy Kindel, MD, PhD

Grant Title:
The effect of sleeve gastrectomy on obesity induced heart failure in rats

Currently in progress

Hungness

Eric S. Hungness, MD, FACS

Grant Title:
Effect of Laparoscopic Sleeve Gastrectomy on 
Esophagogastric Junction Distensibility

Currently in progress

AliMohamed R. Ali, MD, FACS

Grant Title:
Gut Microbiota and Their Xeno-Metabolites: Associations  with Metabolic Health of Women Undergoing Roux-En-Y Gastric Bypass

Currently in progress

Funk-LujeLuke Funk, MD, MPH

Grant Project:
Understanding Primary Care Physician Perspectives on Severe Obesity

Currently in progress

Sabrena-NoriaSabrena Noria, MD, PhD

Grant Project:
Determinants of Diabetes Remission after
Bariatric Surgery and the Role of Gut Hormones and Aging

Currently in progress

Research-SteeleKimberley Steele, MD, PhD

Grant Project:
Neurobiologic alterations induced by bariatric surgery: the gut-brain axis and its relationship to weight loss

Currently in progress

Research-Brethauer Stacy A. Brethauer, MD

Grant Project:
Obesity-Induced Diabetes – Searchig for a Cure Through Bariatric Surgery

Currently in progress

Research-MulJoram D. Mul, MD
(Seeley & Inge Co-PIs)

Grant Project:
Melanocortin Receptor-4 Function is Critical for Energy Homeostasis changes following vertical sleeve Gastrectomy

Currently in progress

Research-RaumWilliam Raum, MD, PhD

Grant Project:
Treatment of Low Metabolic Rates and Low Lean body Mass after Baritatric Surgery

Currently in progress

Research-PryorAurora Pryor, MD 

Grant Project:
Early intervention in patients with predicted poor long-term outcome following laparoscopic Roux-en-Y gastric bypass: a prospective randomized study.

Currently in progress

Research-RichardsWilliam O. Richards, MD 

Grant Project:
Vascular Endothelium Changes after Bariatric Surgery

Presentation:
Bariatric surgery improves the numbers of late outgrowth endothelial progenitor cells ‐‐ Abstract submitted and accepted for oral presentation at ASMBS 2013 Annual Meeting/Obesity Week.

Research-DeUgarteDaniel DeUgarte, MD
David Geffen School of Medicine UCLA

Grant Project:
Impact of Metabolic/Bariatric Surgery on Diet-Induced Childhood Obesity: Implications for Long-Term Health and Offspring Metabolic Phenotype 

Publications:

  • Metabolic Effects of sleeve gastrectomy in a female rat model of diet‐induced obesity. SOARD 7 (2011) 372‐416
  • Risk factors for morbidity and mortality in pediatric patients with peritoneal dialysis catheters. Journal of Pediatric Surgery 2013 48(1):197‐202

Presentations:

  • Impact of sleeve gastrectomy on markers of bone metabolism in a female rat model of diet‐induced obesity. Plenary session. ASMBS, Orlando, FL. Jun 16, 2011
  • The role of bariatric surgery in Adolescent Obesity. UCLA Pediatric Gastroenterology Lecture. Lost Angeles, CA. September 9, 2011.

Research-PetersMichael B. Peters, MD
Christiana Institute for Advanced Surgery, PA

Grant Project:
Autonomic Nervous System Function and Novel Determinants of Glucose Gomeostasis Following Bariatric Surgery  

Publications:
Effects of surgically induced weight loss by rouxen‐Y gastric bypass on cardiovascular autonomic nerve function. SOARD 9 (2013) 221‐228

Presentations:
Effect of osteocalcin on short‐term glucose homeostasis before and after surgery‐induced weight loss – ASMBS 2011 Annual Meeting PosterSession

Research-StillChristopher  D. Still, DO, FACN, FACP

Grant Project:
Identification of Moleculear Markers for NASH

Currently in progress

Research-EvansRonald K. Evans, PhD
Virginia Commonwealth University, Richmond, VA

Grant Project:
Metabolic and Cardiovascular Disease Risk Reducation Following Gastric Bypass Surgery:  The Role of Endothelial Progenitor Cells in Vascular Health 

Currently in progress

Research-PattiMary-Elizabeth Patti, MD
Joslin Diabetes Center, Boston, MA

Grant Project:
Hyperinsulinemic Hypoglycemia Following Gastric Bypass:  Pathophysiology and Molecular Mechanism 

Currently in progress

Research-RideoutDrew Rideout, MD
University of South Florida, Tampa, FL

Grant Project:
Adiponectin Improves Steatohepatitis in Obese Rats After Roux-en-Y Gastric Bypass

Publications:

  • Downregulation of Adiponectin/AdipoR2 is Associated with Steatohepatitis in Obese Mice. J Gastrointest Surg. 2009;13(11):2043–9
  • Does LKB1 mediate activation of hepatic AMPprotein kinase (AMPK) and Sirtuin1 (SIRT1) after Roux‐en‐Y Gastric Bypass in obese rats? J Gastrointest Surg. 2010 Feb;14(2):221‐8
  • Involvement of Adiponectin‐SIRT1‐AMPK Signaling in the Protective Action of Rosiglitazone against Alcoholic Fatty Liver in Mice. Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G364‐74
  • RYGB Alters TNF‐alpha but not Adiponectin Signaling in the Immediate Postoperative Period in Obese Rats. SOARD 5 (2009) S1‐S23
  • Diet‐induced obesity associated with steatosis, oxidative stress, and inflammation in liver. SOARD 8 (2012) 73‐83

Presentations:
11 presentations at national surgical conferences including annual meetings for the: 2008 & 2009 American College of Surgeons, 2009 Academic Surgical Congress (AAS/SUS), 2008 & 2009 Digestive Disease Week (SSAT), 2009 & 2010 ASMBS, and 2009 American Academy of Pediatrics.

Research-KalarchianMelissa Kalarchian, PhD
Western Psychiatric Institute & Clinic, Pittsburgh School of Medicine

Grant Project:
Optimizing Longterm Weight Control after Bariatric Surgery

Publications:

  • Optimizing long‐term weight control after bariatric surgery: A pilot study. SOARD 8 (2012) 710‐716
  • Physical activity and physical function in individuals post‐bariatric Surgery. Obes Surg. 2011; 21(8)1243‐1249. Pub Med PMID: 21153567.

Presentations:
Optimizing long‐term weight control after bariatric surgery. Masters Course in Behavioral Health, ASMBS 2008 Annual Meeting

Research-SarwerDavid B. Sarwer, PhD
University of Pennsylvania, Dept of Weight & Eating Disorders

Grant Project:
Improvements in Reproductive Status Following Bariatric Surgery

Publications:
Manuscripts currently under review: Sexual Functioning and sex hormones in persons with extreme obesity and seeking surgical and nonsurgical weight loss SOARD 11  (2013)

Presentations:

  • Examination of Reproductive and Psychosocial Functioning: A comparative study of women seeking bariatric surgery and behavioral weight loss – ASMBS 2010 Annual Meeting
  • Results on the relationship between reproductive biomarkers, adipokines, and measures of adiposity ‐‐ Annual meeting of the American Society for Reproductive Medicine October 2010.
  • Changes in Reproductive and Psychosocial Functioning in Obese Women Following Bariatric Surgery or Surgery or Lifestyle Modification – ASMBS 2012 Annual Meeting

Research-BesslerMarc Bessler, MD
New York Presbyterian Hospital

Grant Project:
Effects of Obesity on Airway Inflammation andAsthma

Publications:
Exhaled nitric oxide in obese asthmatics and obese non‐asthmatics. SOARD 5 (2009) S67‐S70

Presentations:
Exhaled nitric oxide in obese asthmatics and obese non‐asthmatics. Research presented in Students/Residents/Fellows Session of ASMBS 2009 Annual Meeting

Research-RogersStanley Rogers, MD
UCSF Department of Surgery

Grant Project:
Nutrient absorption in morbidly obese patients before and after gastric bypass surgery

Publications:

  • Laparoscopic Bariatric Surgery Improves candidacy in morbidly obese patients. Abstract. SOARD 3 (2007) 277‐298
  • Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation. SOARD 4 (2008) 159‐165

Presentations:
Laparoscopic Bariatric Surgery Improves candidacy in morbidly obese patients. Research presented in Plenary Session, Comorbidities at ASMBS 2007 Annual Meeting

Research-SalehiMarzieh Salehi, MD
University of Cincinnati College of Medicine,  Dept. of Medicine, Division of Endocrinology

Grant Project:
The role of glucagon like peptide1 in glucose metabolism and weight loss following gastric bypass surgery

Publications :
Gastric Bypass surgery enhances glucagon‐like peptide 1stimulated postprandial insulin secretion in humans. Diabetes 60(9): 2308‐14, 2011

Presentations:

  • Patients with hypoglycemia following Roux‐en‐Y gastric bypass surgery have enhanced incretin secretion mediated by GLP‐1 action. Endocrine Society Annual Meeting 2008
  • The role of GLP‐1 in hypoglycemic syndrome. Joslin Diabetes Center International Symposium 2008
  • Insulin secretion mediated by GLP‐1 action is enhanced following Roux‐en‐Y gastric bypass surgery. American Diabetes Association Scientific Session 2009
  • Bariatric Surgery: Mechanisms of surgery‐based therapy for obesity and diabetes, more than rearranging the plumbing. Symposium : Obesity and its complications. Endocrine Society Annual Meeting 2012.
  • Bariatric Surgeries & Diabetes Resolution. The Ohio ACP Chapter Scientific Meeting 2012
  • Altered glucose metabolism after bariatric surgeries: what every surgeon should know. The Ohio ASMBS Chapter 2013

Research-CottamDaniel R. Cottam, MD
Surgical Weightloss Center of Utah

Grant Project:
Oncologic Effects of Morbid Obesity on Apoptotic Markers and Turmor Growth Factors Before and After Roux-en-Y Gastric Bypass and Adjustable Gastric Banding 

Publications:
Tumor growth factor expression in obesity and changes in expression with weight loss: another cause of increased virulence and incidence of cancer in obesity. SOARD 6 (2010) 538‐541

Presentations:
Tumor growth factor expression in obesity and changes in expression with weight loss: another cause of increased virulence and incidence of cancer in obesity. Abstract presented at ASMBS 2009 Annual Meeting

Samer Mattar, MD
“Thromboprophylaxis in the Morbidly Obese Weight-based dosing of Fondaparinux” 

Samer Mattar, MD 

Pharmacodynamic Study of Fondaparinux Dosing in the Morbidly Obese